Ontology highlight
ABSTRACT:
SUBMITTER: Jitsuki S
PROVIDER: S-EPMC3503249 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Jitsuki Susumu S Takemoto Kiwamu K Kawasaki Taisuke T Tada Hirobumi H Takahashi Aoi A Becamel Carine C Sano Akane A Yuzaki Michisuke M Zukin R Suzanne RS Ziff Edward B EB Kessels Helmut W HW Takahashi Takuya T
Neuron 20110201 4
Loss of one type of sensory input can cause improved functionality of other sensory systems. Whereas this form of plasticity, cross-modal plasticity, is well established, the molecular and cellular mechanisms underlying it are still unclear. Here, we show that visual deprivation (VD) increases extracellular serotonin in the juvenile rat barrel cortex. This increase in serotonin levels facilitates synaptic strengthening at layer 4 to layer 2/3 synapses within the barrel cortex. Upon VD, whisker e ...[more]