Ontology highlight
ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC3505255 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Sun Xiaofeng X Han Lihui L Seth Pankaj P Bian Shu S Li Linglin L Csizmadia Eva E Junger Wolfgang G WG Schmelzle Moritz M Usheva Anny A Tapper Elliot B EB Baffy Gyorgy G Sukhatme Vikas P VP Wu Yan Y Robson Simon C SC
Hepatology (Baltimore, Md.) 20130101 1
<h4>Unlabelled</h4>Liver cancer is associated with chronic inflammation, which is linked to immune dysregulation, disordered metabolism, and aberrant cell proliferation. Nucleoside triphosphate diphosphohydrolase-1; (CD39/ENTPD1) is an ectonucleotidase that regulates extracellular nucleotide/nucleoside concentrations by scavenging nucleotides to ultimately generate adenosine. These properties inhibit antitumor immune responses and promote angiogenesis, being permissive for the growth of transpla ...[more]