Host remodeling of the gut microbiome and metabolic changes during pregnancy.
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ABSTRACT:
SUBMITTER: Koren O
PROVIDER: S-EPMC3505857 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Publications
Host remodeling of the gut microbiome and metabolic changes during pregnancy.
Koren Omry O Goodrich Julia K JK Cullender Tyler C TC Spor Aymé A Laitinen Kirsi K Bäckhed Helene Kling HK Gonzalez Antonio A Werner Jeffrey J JJ Angenent Largus T LT Knight Rob R Bäckhed Fredrik F Isolauri Erika E Salminen Seppo S Ley Ruth E RE
Cell 20120801 3
Many of the immune and metabolic changes occurring during normal pregnancy also describe metabolic syndrome. Gut microbiota can cause symptoms of metabolic syndrome in nonpregnant hosts. Here, to explore their role in pregnancy, we characterized fecal bacteria of 91 pregnant women of varying prepregnancy BMIs and gestational diabetes status and their infants. Similarities between infant-mother microbiotas increased with children's age, and the infant microbiota was unaffected by mother's health ...[more]
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