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A quantitative analysis software tool for mass spectrometry-based proteomics.

ABSTRACT: We describe Census, a quantitative software tool compatible with many labeling strategies as well as with label-free analyses, single-stage mass spectrometry (MS1) and tandem mass spectrometry (MS/MS) scans, and high- and low-resolution mass spectrometry data. Census uses robust algorithms to address poor-quality measurements and improve quantitative efficiency, and it can support several input file formats. We tested Census with stable-isotope labeling analyses as well as label-free analyses.

SUBMITTER: Park SK

PROVIDER: S-EPMC3509211 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature

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A quantitative analysis software tool for mass spectrometry-based proteomics.

Park Sung Kyu SK Venable John D JD Xu Tao T Yates John R JR

Nature methods 20080316 4

We describe Census, a quantitative software tool compatible with many labeling strategies as well as with label-free analyses, single-stage mass spectrometry (MS1) and tandem mass spectrometry (MS/MS) scans, and high- and low-resolution mass spectrometry data. Census uses robust algorithms to address poor-quality measurements and improve quantitative efficiency, and it can support several input file formats. We tested Census with stable-isotope labeling analyses as well as label-free analyses. ...[more]

PMID: 18345006

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