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ABSTRACT: Background
Reducing symptom burden is paramount at the end-of-life, but typically considered secondary to risk factor control in chronic disease, such as diabetes. Little is known about the symptom burden experienced by adults with type 2 diabetes and the need for symptom palliation.Objective
To examine pain and non-pain symptoms of adults with type 2 diabetes over the disease course - at varying time points before death and by age.Design
Survey follow-up study.Participants
13,171 adults with type 2 diabetes, aged 30-75 years, from Kaiser Permanente, Northern California, who answered a baseline symptom survey in 2005-2006.Main measures
Pain and non-pain symptoms were identified by self-report and medical record data. Survival status from baseline was categorized into ? 6, >6-24, or alive >24 months.Key results
Mean age was 60 years; 48 % were women, and 43 % were non-white. Acute pain was prevalent (41.8 %) and 39.7 % reported chronic pain, 24.6 % fatigue, 23.7 % neuropathy, 23.5 % depression, 24.2 % insomnia, and 15.6 % physical/emotional disability. Symptom burden was prevalent in all survival status categories, but was more prevalent among those with shorter survival, p24 months reported more physical symptoms such as acute pain and dyspnea, whereas participants <60 years reported more psychosocial symptoms, such as depressed mood and insomnia. Adjustment for duration of diabetes and comorbidity reduced the association between age and pain, but did not otherwise change our results.Conclusions
In a diverse cohort of adults with type 2 diabetes, pain and non-pain symptoms were common among all patients, not only among those near the end of life. However, symptoms were more prevalent among patients with shorter survival. Older adults reported more physical symptoms, whereas younger adults reported more psychosocial symptoms. Diabetes care management should include not only good cardiometabolic control, but also symptom palliation across the disease course.
SUBMITTER: Sudore RL
PROVIDER: S-EPMC3509316 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Sudore Rebecca L RL Karter Andrew J AJ Huang Elbert S ES Moffet Howard H HH Laiteerapong Neda N Schenker Yael Y Adams Alyce A Whitmer Rachel A RA Liu Jennifer Y JY Miao Yinghui Y John Priya M PM Schillinger Dean D
Journal of general internal medicine 20120802 12
<h4>Background</h4>Reducing symptom burden is paramount at the end-of-life, but typically considered secondary to risk factor control in chronic disease, such as diabetes. Little is known about the symptom burden experienced by adults with type 2 diabetes and the need for symptom palliation.<h4>Objective</h4>To examine pain and non-pain symptoms of adults with type 2 diabetes over the disease course - at varying time points before death and by age.<h4>Design</h4>Survey follow-up study.<h4>Partic ...[more]