Ontology highlight
ABSTRACT:
SUBMITTER: Soica C
PROVIDER: S-EPMC3509624 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Soica Codruta C Dehelean Cristina C Danciu Corina C Wang Hai Ming HM Wenz Gerhard G Ambrus Rita R Bojin Florina F Anghel Mariana M
International journal of molecular sciences 20121115 11
Given the present high incidence of melanoma and skin cancer, interest in potential drugs of plant origin has increased significantly. Pentacyclic lupane-type triterpenes are widely distributed in plants, offering numerous pharmacological benefits. Betulin is an important compound in the bark of Betula pendula Roth and has important therapeutic properties, including antitumor activities. Its biological effect is limited by its poor water solubility, which can be improved by cyclodextrin complexa ...[more]