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ABSTRACT:
SUBMITTER: Sugiman-Marangos S
PROVIDER: S-EPMC3509982 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Sugiman-Marangos Seiji S Junop Murray M
Acta crystallographica. Section F, Structural biology and crystallization communications 20121114 Pt 12
The remarkable ability of members of the Deinococcus family to recover from extreme DNA damage is in part owing to their robust DNA-repair mechanisms. Of particular interest is their ability to repair hundreds of double-strand DNA breakages through a rapid and efficient mechanism involving novel proteins that are uniquely found in Deinococcus spp. One such protein, DdrB, which is thought to play a role early in DSB repair, has been crystallized in complex with ssDNA and data have been collected ...[more]