Ontology highlight
ABSTRACT:
SUBMITTER: Sket P
PROVIDER: S-EPMC3510487 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Šket Primoz P Virgilio Antonella A Esposito Veronica V Galeone Aldo A Plavec Janez J
Nucleic acids research 20120912 21
Nuclear magnetic resonance study of G-quadruplex structures formed by d(TG(3)T) and its modified analogs containing a 5'-5' or 3'-3' inversion of polarity sites, namely d(3'TG5'-5'G(2)T3'), d(3'T5'-5'G(3)T3') and d(5'TG3'-3'G(2)T5') demonstrates formation of G-quadruplex structures with tetrameric topology and distinct cation-binding preferences. All oligonucleotides are able to form quadruplex structures with two binding sites, although the modified oligonucleotides also form, in variable amoun ...[more]