Ontology highlight
ABSTRACT:
SUBMITTER: Lambert B
PROVIDER: S-EPMC3514159 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Lambert Barbara B Vandeputte Julie J Remacle Sophie S Bergiers Isabelle I Simonis Nicolas N Twizere Jean-Claude JC Vidal Marc M Rezsohazy René R
BMC developmental biology 20121022
<h4>Background</h4>Hox proteins are transcription factors involved in crucial processes during animal development. Their mode of action remains scantily documented. While other families of transcription factors, like Smad or Stat, are known cell signaling transducers, such a function has never been squarely addressed for Hox proteins.<h4>Results</h4>To investigate the mode of action of mammalian Hoxa1, we characterized its interactome by a systematic yeast two-hybrid screening against ~12,200 OR ...[more]