Fast and accurate low-dimensional reduction of biophysically detailed neuron models.
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ABSTRACT:
SUBMITTER: Marasco A
PROVIDER: S-EPMC3514644 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Fast and accurate low-dimensional reduction of biophysically detailed neuron models.
Marasco Addolorata A Limongiello Alessandro A Migliore Michele M
Scientific reports 20121205
Realistic modeling of neurons are quite successful in complementing traditional experimental techniques. However, their networks require a computational power beyond the capabilities of current supercomputers, and the methods used so far to reduce their complexity do not take into account the key features of the cells nor critical physiological properties. Here we introduce a new, automatic and fast method to map realistic neurons into equivalent reduced models running up to > 40 times faster wh ...[more]
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