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Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43.

ABSTRACT: THE TITLE COMPOUND [SYSTEMATIC NAME: (3S,8aS)-3-isopropyl-hexa-hydro-pyrrolo-[1,2-a]pyrazine-1,4-dione], C(10)H(16)N(2)O(2),, is a newly isolated cyclic dipeptide from Burkholderia thailandensis MSMB43. There are two independent mol-ecules in the asymmetric unit. Two C atoms and their attached H atoms in the five-membered ring of one of the mol-ecules are disordered over two sets of sites in a 0.715?(5):0.285?(5) ratio. The two independent mol-ecules have the same configuration and the absolute configurations of the chiral centers were determined based on the observation of anomalous dispersion. In the crystal, two types of N-H?O hydrogen bonds link pairs of independent mol-ecules.

SUBMITTER: Liu XY

PROVIDER: S-EPMC3515274 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43.

Liu Xiang-Yang XY Wang Cheng C Cheng Yi-Qiang YQ

Acta crystallographica. Section E, Structure reports online 20121020 Pt 11

THE TITLE COMPOUND [SYSTEMATIC NAME: (3S,8aS)-3-isopropyl-hexa-hydro-pyrrolo-[1,2-a]pyrazine-1,4-dione], C(10)H(16)N(2)O(2),, is a newly isolated cyclic dipeptide from Burkholderia thailandensis MSMB43. There are two independent mol-ecules in the asymmetric unit. Two C atoms and their attached H atoms in the five-membered ring of one of the mol-ecules are disordered over two sets of sites in a 0.715 (5):0.285 (5) ratio. The two independent mol-ecules have the same configuration and the absolute ...[more]

PMID: 23284494

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