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10'-Chloro-3',4'-dihydro-2'H-spiro-[cyclo-propane-1,7'(6'H)-pyrimido[2,1-a]isoquinolin]-6'-one.

ABSTRACT: In the title compound, C(14)H(13)ClN(2)O, the fused hydro-pyrimidine ring adopts an envelope conformation with one of the methyl-ene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44?(11)°. In the crystal, mol-ecules are linked by a weak C-H?? inter-action, forming a helical chain along the c axis.

SUBMITTER: Okuda K

PROVIDER: S-EPMC3515329 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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10'-Chloro-3',4'-dihydro-2'H-spiro-[cyclo-propane-1,7'(6'H)-pyrimido[2,1-a]isoquinolin]-6'-one.

Okuda Kensuke K Hirota Takashi T Nishina Yuta Y Ishida Hiroyuki H

Acta crystallographica. Section E, Structure reports online 20121031 Pt 11

In the title compound, C(14)H(13)ClN(2)O, the fused hydro-pyrimidine ring adopts an envelope conformation with one of the methyl-ene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44 (11)°. In the crystal, mol-ecules are linked by a weak C-H⋯π inter-action, forming a helical chain along the c axis. ...[more]

PMID: 23284549

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