Ontology highlight
ABSTRACT:
SUBMITTER: Zou Z
PROVIDER: S-EPMC3515374 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Zou Zhisong Z Zeng Fuxing F Zhang Lu L Niu Liwen L Teng Maikun M Li Xu X
Acta crystallographica. Section F, Structural biology and crystallization communications 20121030 Pt 11
Phospholipases A2 (PLA2s) are the major component of snake venoms and exert a variety of relevant toxic actions such as neurotoxicity and myotoxicity, amongst others. An acidic PLA2, here named AhV_aPA, was purified from Agkistrodon halys pallas venom by means of a three-step chromatographic procedure. AhV_aPA migrated as a single band on SDS-PAGE gels, with a molecular weight of about 14 kDa. Like other acidic aPLA2s, AhV_aPA has high enzymatic activity. Tension measurements of mouse thoracic a ...[more]