A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
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ABSTRACT:
SUBMITTER: Hayakawa M
PROVIDER: S-EPMC3517015 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
Hayakawa Masahiko M Toda Narihiro N Carrillo Nancy N Thornburg Natalie J NJ Crowe James E JE Barbas Carlos F CF
Chembiochem : a European journal of chemical biology 20120910 15
Programming an anti-flu strategy: A new and potent neuraminidase inhibitor that maintains long-term systemic exposure of an antibody and the therapeutic activity of the neuraminadase inhibitor zanamivir has been created. This strategy could provide a promising new class of influenza A drugs for therapy and prophylaxis, and validates enzyme inhibitors as programming agents in synthetic immunology. ...[more]
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