Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC3517037 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Xu Xinfang X Zavalij Peter Y PY Doyle Michael P MP
Angewandte Chemie (International ed. in English) 20120903 39
A versatile cascade of reactions, triggered by Rh(II)-catalyzed diazo decomposition followed by a vinylogous N-H insertion/Lewis acid catalyzed Mannich addition, that produces highly substituted 1,2,3,6-tetrahydropyridazines in up to 97 % ee with high yield and diastereocontrol has been developed. ...[more]