The association of the triglyceride-to-HDL cholesterol ratio with insulin resistance in White European and South Asian men and women.

ABSTRACT:

Introduction

There is recent interest surrounding the use of the triglyceride-to-HDL cholesterol ratio as a surrogate marker of insulin resistance in clinical practice, as it may identify people at high risk of developing diabetes or its complications. However, it has been suggested using this lipid ratio may not be appropriate for measuring insulin resistance in African-Americans, particularly women. We investigated if this inconsistency extended to South Asian women in a UK multi-ethnic cohort of White Europeans and South Asians.

Methods

Cross-sectional analysis was done of 729 participants from the ADDITION-Leicester study from 2005 to 2009. The association between tertiles of triglyceride-to-HDL cholesterol ratio to fasting insulin, homeostatic model of assessment for in

SUBMITTER: Mostafa SA 

PROVIDER: S-EPMC3518473 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature