Ontology highlight
ABSTRACT:
SUBMITTER: Dougherty MK
PROVIDER: S-EPMC3518556 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Dougherty Michael K MK Gu Hongbin H Bizzell Joshua J Ramsey Stacy S Gerig Guido G Perkins Diana O DO Belger Aysenil A
Psychiatry research 20121110 2-3
Schizophrenia has been associated with reduced volumes of subcortical structures on magnetic resonance imaging (MRI), but the relation of these reductions to familial risk for the disorder is unclear. We investigated the effect of familial risk for schizophrenia on regional subcortical volumes during adolescence, a period marked by steep maturational changes in brain structure and the emergence of psychotic symptoms. A group of 26 non-help-seeking, first-degree relatives of patients with schizop ...[more]