Surface chemistry-mediated penetration and gold nanorod thermotherapy in multicellular tumor spheroids.
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ABSTRACT:
SUBMITTER: Jin S
PROVIDER: S-EPMC3518646 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Publications
Surface chemistry-mediated penetration and gold nanorod thermotherapy in multicellular tumor spheroids.
Jin Shubin S Ma Xiaowei X Ma Huili H Zheng Kaiyuan K Liu Juan J Hou Shuai S Meng Jie J Wang Paul C PC Wu Xiaochun X Liang Xing-Jie XJ
Nanoscale 20121115 1
We investigated the penetration and thermotherapy efficiency of different surface coated gold nanorods (Au NRs) in multicellular tumor spheroids. The current data show that negatively charged Au NRs, other than positively charged Au NRs, can penetrate deep into the tumor spheroids and achieve a significant thermal therapeutic benefit. ...[more]
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