Ontology highlight
ABSTRACT:
SUBMITTER: Ferguson SM
PROVIDER: S-EPMC3519936 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Ferguson Shawn M SM De Camilli Pietro P
Nature reviews. Molecular cell biology 20120111 2
Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in membrane remodelling, has a critical role in endocytic membrane fission events. The use of complementary approaches, including live-cell imaging, cell-free studies, X-ray crystallography and genetic studies in mice, has greatly advanced our understanding of the mechanisms by which dynamin acts, its essential roles in cell physiology and the specific function of different dynamin isoforms. In addition, several ...[more]