Ontology highlight
ABSTRACT:
SUBMITTER: Romee R
PROVIDER: S-EPMC3520618 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Blood 20120914 24
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent studies in mice have shown that stimulation of NK cells with cytokines or in the context of a viral infection results in memory-like properties. We hypothesized that human NK cells exhibit such memory-like properties with an enhanced recall response after cytokine preactivation. In the present study, we show that human NK cells preactivated briefly with cytokine combin ...[more]