Ontology highlight
ABSTRACT:
SUBMITTER: Sochacki KA
PROVIDER: S-EPMC3521636 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Sochacki Kem A KA Larson Ben T BT Sengupta Deepali C DC Daniels Mathew P MP Shtengel Gleb G Hess Harald F HF Taraska Justin W JW
Nature communications 20120101
The molecular mechanism responsible for capturing, sorting and retrieving vesicle membrane proteins following triggered exocytosis is not understood. Here we image the post-fusion release and then capture of a vesicle membrane protein, the vesicular acetylcholine transporter, from single vesicles in living neuroendocrine cells. We combine these measurements with super-resolution interferometric photo-activation localization microscopy and electron microscopy, and modelling to map the nanometer-s ...[more]