Ontology highlight
ABSTRACT:
SUBMITTER: Budczies J
PROVIDER: S-EPMC3522617 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Budczies Jan J Klauschen Frederick F Sinn Bruno V BV Győrffy Balázs B Schmitt Wolfgang D WD Darb-Esfahani Silvia S Denkert Carsten C
PloS one 20121214 12
Gene or protein expression data are usually represented by metric or at least ordinal variables. In order to translate a continuous variable into a clinical decision, it is necessary to determine a cutoff point and to stratify patients into two groups each requiring a different kind of treatment. Currently, there is no standard method or standard software for biomarker cutoff determination. Therefore, we developed Cutoff Finder, a bundle of optimization and visualization methods for cutoff deter ...[more]