Ontology highlight
ABSTRACT:
SUBMITTER: Albertazzi L
PROVIDER: S-EPMC3524974 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Biomacromolecules 20121127 12
Hybrid dendritic-linear block copolymers based on a 4-arm poly(ethylene glycol) (PEG) core were synthesized using an accelerated AB2/CD2 dendritic growth approach through orthogonal amine/epoxy and thiol-yne chemistries. The biological activity of these 4-arm and the corresponding 2-arm hybrid dendrimers revealed an enhanced, dendritic effect with an exponential increase in cell internalization concomitant with increasing amine end groups and low cytotoxicity. Furthermore, the ability of these h ...[more]