Associations of welding and manganese exposure with Parkinson disease: review and meta-analysis.

ABSTRACT:

Objective

To examine associations of welding and manganese exposure with Parkinson disease (PD) using meta-analyses of data from cohort, case-control, and mortality studies.

Methods

Epidemiologic studies related to welding or manganese exposure and PD were identified in a PubMed search, article references, published reviews, and abstracts. Inclusion criteria were 1) cohort, case-control, or mortality study with relative risk (RR), odds ratio (OR), or mortality OR (MOR) and 95 confidence intervals (95% CI); 2) RR, OR, and MOR matched or adjusted for age and sex; 3) valid study design and analysis. When participants of a study were a subgroup of those in a larger study, only results of the larger study were included to assure independence of datasets. Pooled RR/OR estimates an

SUBMITTER: Mortimer JA 

PROVIDER: S-EPMC3525308 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature