Gender, body mass index, and PPAR? polymorphism are good indicators in hyperuricemia prediction for Han Chinese.
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ABSTRACT:
SUBMITTER: Lee MF
PROVIDER: S-EPMC3525899 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
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Gender, body mass index, and PPARγ polymorphism are good indicators in hyperuricemia prediction for Han Chinese.
Lee Ming-Fen MF Liou Tsan-Hon TH Wang Weu W Pan Wen-Harn WH Lee Wei-Jei WJ Hsu Chung-Tan CT Wu Suh-Fen SF Chen Hsin-Hung HH
Genetic testing and molecular biomarkers 20130101 1
Hyperuricemia is closely associated with obesity and metabolic abnormalities, which is also an independent risk factor for cardiovascular diseases. The PPARγ gene, which is linked to obesity and metabolic abnormalities in Han Chinese, might be considered a top candidate gene that is involved in hyperuricemia. This study recruited 457 participants, aged 20-40 years old, to investigate the associations of the PPARγ gene and metabolic parameters with hyperuricemia. Three tag-single nucleotide polym ...[more]
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