Ontology highlight
ABSTRACT:
SUBMITTER: Ji JJ
PROVIDER: S-EPMC3527394 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Ji Juan Juan JJ Chen Lianwan L Duan Xuezhi X Song Xueqin X Su Wenting W Zhang Peng P Li Li L Bai Shuyun S Sun Yingchun Y Inagaki Nobuya N
PloS one 20121220 12
Whether large conductance Ca(2+)-activated potassium (BK) channels are present in the substantia nigra pars reticulata (SNr) is a matter of debate. Using the patch-clamp technique, we examined the functional expression of BK channels in neurons of the SNr and showed that the channels were activated or inhibited by internal high-energy phosphates (IHEPs) at positive and negative membrane potentials, respectively. SNr neurons showed membrane potential hyperpolarization under glucose-deprivation co ...[more]