Ontology highlight
ABSTRACT:
SUBMITTER: Castillo JC
PROVIDER: S-EPMC3528259 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Castillo Juan Carlos Quintana JC Vargas Leidy Johana LJ Segura Cesar C Gutiérrez José María JM Pérez Juan Carlos Alarcón JC
Toxins 20121214 12
The antimicrobial and antiparasite activity of phospholipase A(2) (PLA(2)) from snakes and bees has been extensively explored. We studied the antiplasmodial effect of the whole venom of the snake Bothrops asper and of two fractions purified by ion-exchange chromatography: one containing catalytically-active phospholipases A(2) (PLA(2)) (fraction V) and another containing a PLA(2) homologue devoid of enzymatic activity (fraction VI). The antiplasmodial effect was assessed on in vitro cultures of ...[more]