Ontology highlight
ABSTRACT:
SUBMITTER: Belogurov AA
PROVIDER: S-EPMC3528315 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Belogurov Alexey A AA Stepanov Alexey V AV Smirnov Ivan V IV Melamed Dobroslav D Bacon Andrew A Mamedov Azad E AE Boitsov Vitali M VM Sashchenko Lidia P LP Ponomarenko Natalia A NA Sharanova Svetlana N SN Boyko Alexey N AN Dubina Michael V MV Friboulet Alain A Genkin Dmitry D DD Gabibov Alexander G AG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121009 1
Multiple sclerosis (MS) is a severe inflammatory and neurodegenerative disease with an autoimmune background. Despite the variety of therapeutics available against MS, the development of novel approaches to its treatment is of high importance in modern pharmaceutics. In this study, experimental autoimmune encephalomyelitis (EAE) in Dark Agouti rats has been treated with immunodominant peptides of the myelin basic protein (MBP) encapsulated in mannosylated small unilamellar vesicles. The results ...[more]