Ontology highlight
ABSTRACT:
SUBMITTER: Long J
PROVIDER: S-EPMC3531288 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Long Juexuan J Junkin Michael M Wong Pak Kin PK Hoying James J Deymier Pierre P
PLoS computational biology 20121227 12
In this paper, we present a combined theoretical and experimental study of the propagation of calcium signals in multicellular structures composed of human endothelial cells. We consider multicellular structures composed of a single chain of cells as well as a chain of cells with a side branch, namely a "T" structure. In the experiments, we investigate the result of applying mechano-stimulation to induce signaling in the form of calcium waves along the chain and the effect of single and dual sti ...[more]