Chapter 10: Mining genome-wide genetic markers.
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ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC3531292 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Chapter 10: Mining genome-wide genetic markers.
Zhang Xiang X Huang Shunping S Zhang Zhaojun Z Wang Wei W
PLoS computational biology 20121227 12
Genome-wide association study (GWAS) aims to discover genetic factors underlying phenotypic traits. The large number of genetic factors poses both computational and statistical challenges. Various computational approaches have been developed for large scale GWAS. In this chapter, we will discuss several widely used computational approaches in GWAS. The following topics will be covered: (1) An introduction to the background of GWAS. (2) The existing computational approaches that are widely used i ...[more]
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