Ontology highlight
ABSTRACT:
SUBMITTER: Zdrazil B
PROVIDER: S-EPMC3531886 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Zdrazil Barbara B Pinto Marta M Vasanthanathan Poongavanam P Williams Antony J AJ Balderud Linda Zander LZ Engkvist Ola O Chichester Christine C Hersey Anne A Overington John P JP Ecker Gerhard F GF
Molecular informatics 20120807 8
Huge amounts of small compound bioactivity data have been entering the public domain as a consequence of open innovation initiatives. It is now the time to carefully analyse existing bioassay data and give it a systematic structure. Our study aims to annotate prominent in vitro assays used for the determination of bioactivities of human P-glycoprotein inhibitors and substrates as they are represented in the ChEMBL and TP-search open source databases. Furthermore, the ability of data, determined ...[more]