Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC3534063 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Wang Hui H Chen Shusu S Zhang Juan J Rothenbacher Francesca P FP Jiang Tiantian T Kan Biao B Zhong Zengtao Z Zhu Jun J
PloS one 20121231 12
Oxidative stress is a major challenge faced by bacteria. Many bacteria control oxidative stress resistance pathways through the transcriptional regulator OxyR. The human pathogen Vibrio cholerae is a Gram-negative bacterium that is the causative agent of cholera. V. cholerae lives in both aquatic environments and human small intestines, two environments in which it encounters reactive oxygen species (ROS). To study how V. cholerae responds to oxidative stress, we constructed an in-frame oxyR del ...[more]