Ontology highlight
ABSTRACT:
SUBMITTER: Gadelha A
PROVIDER: S-EPMC3534097 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Gadelha Ary A Ota Vanessa Kiyomi VK Cano Jose Paya JP Melaragno Maria Isabel MI Smith Marilia A C MA de Jesus Mari Jair J Bressan Rodrigo A RA Belangero Sintia Iole SI Breen Gerome G
PloS one 20121231 12
We report analyses of a Brazilian study of early onset schizophrenia (BEOS) families. We genotyped 22 members of 4 families on a linkage SNP array and report here non-parametric linkage analyses using MERLIN® software. We found suggestive evidence for linkage on two chromosomal regions, 13q32 and 11p15.4. A LOD score of 2.71 was observed at 13q32 with a one LOD interval extending from 60.63-92.35 cM. From simulations, this LOD score gave a genome-wide empirical corrected p = 0.33, after accounti ...[more]