Ontology highlight
ABSTRACT:
SUBMITTER: Wei JC
PROVIDER: S-EPMC3537770 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Wei James Cheng-Chung JC Hsu Yu-Wen YW Hung Kuo-Sheng KS Wong Ruey-Hong RH Huang Chun-Huang CH Liu Yi-Tzu YT Guo Yuh-Cherng YC Ikegawa Shiro S Chang Wei-Chiao WC
PloS one 20130104 1
Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints. However, the development of anklosing spondylitis is unclear. Human leukocyte antigens HLA-B27 and ERAP1 have been widely reported to be associated with AS susceptibility. A recent genome-wide association study (GWAS) showed that two new susceptibility loci between EDIL3 and HAPLN1 at 5q14.3 (rs4552569) and within ANO6 at 12q12 (rs17095830) contribute to the risk of AS in Han Chinese. In ...[more]