Ontology highlight
ABSTRACT:
SUBMITTER: DeLuca RJ
PROVIDER: S-EPMC3539300 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Organic letters 20121219 1
A palladium-catalyzed hydroalkylation reaction of protected allylic alcohols using alkylzinc bromide reagents is reported. This account includes numerous allylic, homoallylic, and bishomoallylic alcohol derivatives, all with a uniform selectivity of >20:1 for the anti-Markovnikov product. The reaction features the ability to deliver enantiomerically enriched alcohols in unfunctionalized regions, which results from the catalyst avoiding β-hydride elimination at the allylic position. ...[more]