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Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin IV and chetracin B.

ABSTRACT: Westerdykella reniformis Ebead & Overy sp. nov. is described based on morphology and phylogenetic analyses using ITS, nLSU rDNA, and ?-tubulin gene sequences. Westerdykella reniformis is characterized by the production of cleistothecioid ascomata, containing small globose to subglobose asci with 32, aseptate, dark colored, pronouncedly reniform ascospores having a concave central groove. The isolate was obtained from a red alga (Polysiphonia sp.) collected from the tidal zone in Canada at low tide. Organic extracts enriched in extrolites, obtained from fermentation on a rice-based media, inhibited the growth of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), S. warneri, and Proteus vulgaris. Presented here is the identification of the compounds responsible for the observed antimicrobial activity, the taxonomic description of W. reniformis, and a dichotomous key to the known species of Westerdykella based on macro- and micromorphological characters.

SUBMITTER: Ebead GA

PROVIDER: S-EPMC3539322 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin IV and chetracin B.

Ebead Ghada A GA Overy David P DP Berrué Fabrice F Kerr Russell G RG

IMA fungus 20121211 2

Westerdykella reniformis Ebead & Overy sp. nov. is described based on morphology and phylogenetic analyses using ITS, nLSU rDNA, and β-tubulin gene sequences. Westerdykella reniformis is characterized by the production of cleistothecioid ascomata, containing small globose to subglobose asci with 32, aseptate, dark colored, pronouncedly reniform ascospores having a concave central groove. The isolate was obtained from a red alga (Polysiphonia sp.) collected from the tidal zone in Canada at low ti ...[more]

PMID: 23355972

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Dataset Information

Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin IV and chetracin B.

Publications

Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin IV and chetracin B.

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