Ontology highlight
ABSTRACT:
SUBMITTER: Phan JH
PROVIDER: S-EPMC3539384 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Phan John H JH Young Andrew N AN Wang May D MD
TheScientificWorldJournal 20121218
Combining multiple microarray datasets increases sample size and leads to improved reproducibility in identification of informative genes and subsequent clinical prediction. Although microarrays have increased the rate of genomic data collection, sample size is still a major issue when identifying informative genetic biomarkers. Because of this, feature selection methods often suffer from false discoveries, resulting in poorly performing predictive models. We develop a simple meta-analysis-based ...[more]