Ontology highlight
ABSTRACT:
SUBMITTER: Saxon AJ
PROVIDER: S-EPMC3543467 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Saxon Andrew J AJ Ling Walter W Hillhouse Maureen M Thomas Christie C Hasson Albert A Ang Alfonso A Doraimani Geetha G Tasissa Gudaye G Lokhnygina Yuliya Y Leimberger Jeff J Bruce R Douglas RD McCarthy John J Wiest Katharina K McLaughlin Paul P Bilangi Richard R Cohen Allan A Woody George G Jacobs Petra P
Drug and alcohol dependence 20120822 1-2
<h4>Background</h4>Buprenorphine/naloxone (BUP) and methadone (MET) are efficacious treatments for opioid dependence, although concerns about a link between BUP and drug-induced hepatitis have been raised. This study compares the effects of BUP and MET on liver health in opioid-dependent participants.<h4>Methods</h4>This was a randomized controlled trial of 1269 opioid-dependent participants seeking treatment at 8 federally licensed opioid treatment programs and followed for up to 32 weeks betwe ...[more]