Ontology highlight
ABSTRACT:
SUBMITTER: Shum M
PROVIDER: S-EPMC3543572 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Shum Michaël M Pinard Sandra S Guimond Marie-Odile MO Labbé Sébastien M SM Roberge Claude C Baillargeon Jean-Patrice JP Langlois Marie-France MF Alterman Mathias M Wallinder Charlotta C Hallberg Anders A Carpentier André C AC Gallo-Payet Nicole N
American journal of physiology. Endocrinology and metabolism 20121113 2
This study was aimed at establishing whether specific activation of angiotensin II (ANG II) type 2 receptor (AT2R) modulates adipocyte differentiation and function. In primary cultures of subcutaneous (SC) and retroperitoneal (RET) preadipocytes, both AT2R and AT1R were expressed at the mRNA and protein level. Cells were stimulated with ANG II or the AT2R agonist C21/M24, alone or in the presence of the AT1R antagonist losartan or the AT2R antagonist PD123,319. During differentiation, C21/M24 in ...[more]