Ontology highlight
ABSTRACT: Aims
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in people with diabetes in South Asia. The CARRS Translation Trial tests the effectiveness, cost-effectiveness, and sustainability of a clinic-based multi-component CVD risk reduction intervention among people with diabetes in India and Pakistan.Methods
We randomly assigned 1146 adults with diabetes recruited from 10 urban clinic sites, to receive usual care by physicians or to receive an integrated multi-component CVD risk reduction intervention. The intervention involves electronic health record management, decision-support prompts to the healthcare team, and the support of a care coordinator to actively facilitate patient and provider adherence to evidence-based guidelines. The primary outcome is a composite of multiple CVD risk factor control (blood glucose and either blood pressure or cholesterol, or all three). Other outcomes include control of the individual CVD risk factors, process and patient-centered measures, cost-effectiveness, and acceptability/feasibility.Conclusion
The CARRS Translation Trial tests a low-cost diabetes care delivery model in urban South Asia to achieve comprehensive cardio-metabolic disease case-management of high-risk patients (clinicaltrials.gov number: NCT01212328).
SUBMITTER: CARRS Trial Writing Group
PROVIDER: S-EPMC3544938 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Shah Seema S Singh Kavita K Ali Mohammed K MK Mohan V V Kadir Muhammad Masood MM Unnikrishnan A G AG Sahay Rakesh Kumar RK Varthakavi Premlata P Dharmalingam Mala M Viswanathan Vijay V Masood Qamar Q Bantwal Ganapathi G Khadgawat Rajesh R Desai Ankush A Sethi Bipin Kumar BK Shivashankar Roopa R Ajay Vamadevan S VS Reddy K Srinath KS Narayan K M Venkat KM Prabhakaran Dorairaj D Tandon Nikhil N
Diabetes research and clinical practice 20121022 2
<h4>Aims</h4>Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in people with diabetes in South Asia. The CARRS Translation Trial tests the effectiveness, cost-effectiveness, and sustainability of a clinic-based multi-component CVD risk reduction intervention among people with diabetes in India and Pakistan.<h4>Methods</h4>We randomly assigned 1146 adults with diabetes recruited from 10 urban clinic sites, to receive usual care by physicians or to receive an integrated ...[more]