Ontology highlight
ABSTRACT:
SUBMITTER: Buckley CE
PROVIDER: S-EPMC3545300 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Buckley Clare E CE Ren Xiaoyun X Ward Laura C LC Girdler Gemma C GC Araya Claudio C Green Mary J MJ Clark Brian S BS Link Brian A BA Clarke Jonathan D W JD
The EMBO journal 20121130 1
By analysing the cellular and subcellular events that occur in the centre of the developing zebrafish neural rod, we have uncovered a novel mechanism of cell polarisation during lumen formation. Cells from each side of the neural rod interdigitate across the tissue midline. This is necessary for localisation of apical junctional proteins to the region where cells intersect the tissue midline. Cells assemble a mirror-symmetric microtubule cytoskeleton around the tissue midline, which is necessary ...[more]