Ontology highlight
ABSTRACT:
SUBMITTER: Brown AE
PROVIDER: S-EPMC3545781 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Brown André E X AE Yemini Eviatar I EI Grundy Laura J LJ Jucikas Tadas T Schafer William R WR
Proceedings of the National Academy of Sciences of the United States of America 20121224 2
Visible phenotypes based on locomotion and posture have played a critical role in understanding the molecular basis of behavior and development in Caenorhabditis elegans and other model organisms. However, it is not known whether these human-defined features capture the most important aspects of behavior for phenotypic comparison or whether they are sufficient to discover new behaviors. Here we show that four basic shapes, or eigenworms, previously described for wild-type worms, also capture mut ...[more]