Ontology highlight
ABSTRACT:
SUBMITTER: Rozhon W
PROVIDER: S-EPMC3546049 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Rozhon Wilfried W Husar Sigrid S Kalaivanan Florian F Khan Mamoona M Idlhammer Markus M Shumilina Daria D Lange Theo T Hoffmann Thomas T Schwab Wilfried W Fujioka Shozo S Poppenberger Brigitte B
PloS one 20130115 1
Brassinosteroids (BRs) are plant steroid hormones with structural similarity to mammalian sex steroids and ecdysteroids from insects. The BRs are synthesized from sterols and are essential regulators of cell division, cell elongation and cell differentiation. In this work we show that voriconazole, an antifungal therapeutic drug used in human and veterinary medicine, severely impairs plant growth by inhibiting sterol-14α-demethylation and thereby interfering with BR production. The plant growth ...[more]