Ontology highlight
ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC3546320 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Wang Tao T Zhang Jiahai J Zhang Xuecheng X Xu Chao C Tu Xiaoming X
Scientific reports 20130116
Streptococcus pneumoniae is a pathogen causing acute respiratory infection, otitis media and some other severe diseases in human. In this study, the solution structure of a bacterial immunoglobulin-like (Big) domain from a putative S. pneumoniae surface protein SP0498 was determined by NMR spectroscopy. SP0498 Big domain adopts an eight-β-strand barrel-like fold, which is different in some aspects from the two-sheet sandwich-like fold of the canonical Ig-like domains. Intriguingly, we identified ...[more]