Brain metastases from colorectal cancer: microenvironment and molecular mechanisms.
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ABSTRACT:
SUBMITTER: Zang YW
PROVIDER: S-EPMC3546661 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Brain metastases from colorectal cancer: microenvironment and molecular mechanisms.
Zang Yi-Wen YW Gu Xiao-Dong XD Xiang Jian-Bin JB Chen Zong-You ZY
International journal of molecular sciences 20121126 12
Colorectal cancer is one of the most common digestive tract malignancies in the world. Owing to the newer and more effective systemic therapies, the life of colorectal cancer patients can be remarkably prolonged, and the incidence of brain metastases is increasing. However, little is known about the underlying mechanisms of brain metastasis from colorectal cancer. Here we review the tumor microenvironment and metastasis associated molecules in brain metastases from colorectal cancer. A further u ...[more]
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