Ontology highlight
ABSTRACT:
SUBMITTER: Sanabani SS
PROVIDER: S-EPMC3547796 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Sanabani Sabri Saeed SS Nukui Youko Y Pereira Juliana J da Costa Antonio Charlys AC de Oliveira Ana Carolina Soares AC Pessôa Rodrigo R Leal Fabio Eudes FE Segurado Aluisio C AC Kallas Esper Georges EG Sabino Ester Cerdeira EC
BMC infectious diseases 20121223
<h4>Background</h4>The Interleukin 28B (IL28B) rs12979860 polymorphisms was recently reported to be associated with the human T-cell leukemia virus type 1 (HTLV-1) proviral load (PvL) and the development of the HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).<h4>Methods</h4>In an attempt to examine this hypothesis, we assessed the association of the rs12979860 genotypes with HTLV-1 PvL levels and clinical status in 112 unrelated Brazilian subjects (81 HTLV-1 asymptomatic carr ...[more]