Dataset Information

Massage improves growth quality by decreasing body fat deposition in male preterm infants.

ABSTRACT:

Objectives

To assess the effect of massage on weight gain and body fat deposition in preterm infants.

Study design

Preterm infants (29-32 weeks) were randomized to the massage group (n = 22, 12 girls, 10 boys) or the control group (n = 22, 12 girls, 10 boys). Treatment was masked with massage or control care administered twice-daily by licensed massage therapists (6 d/wk for 4 weeks). Body weight, length, Ponderal Index (PI), body circumferences, and skinfold thickness (triceps, mid-thigh, and subscapular [SSF]) were measured. Circulating insulin-like growth factor I, leptin, and adiponectin levels were determined by enzyme-linked immunosorbent assay. Daily dietary intake was collected.

Results

Energy and protein intake as well as increase in weight, length, and body circumferences were similar. Male infants in the massage group had smaller PI, triceps skinfold thickness, mid-thigh skinfold thickness, and SSF and increases over time compared with control male infants (P < .05). Female infants in the massage group had larger SSF increases than control female infants (P < .05). Circulating adiponectin increased over time in control group male infants (group × time × sex interaction, P < .01) and was correlated to PI (r = 0.39, P < .01).

Conclusions

Twice-daily massage did not promote greater weight gain in preterm infants. Massage did, however, limit body fat deposition in male preterm infants. Massage decreased circulating adiponectin over time in male infants with higher adiponectin concentrations associated with increased body fat. These findings suggest that massage may improve body fat deposition and, in turn, growth quality of preterm infants in a sex-specific manner.

SUBMITTER: Moyer-Mileur LJ

PROVIDER: S-EPMC3549027 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature

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Publications

Massage improves growth quality by decreasing body fat deposition in male preterm infants.

Moyer-Mileur Laurie J LJ Haley Shannon S Slater Hillarie H Beachy Joanna J Smith Sandra L SL

The Journal of pediatrics 20121011 3

<h4>Objectives</h4>To assess the effect of massage on weight gain and body fat deposition in preterm infants.<h4>Study design</h4>Preterm infants (29-32 weeks) were randomized to the massage group (n = 22, 12 girls, 10 boys) or the control group (n = 22, 12 girls, 10 boys). Treatment was masked with massage or control care administered twice-daily by licensed massage therapists (6 d/wk for 4 weeks). Body weight, length, Ponderal Index (PI), body circumferences, and skinfold thickness (triceps, m ...[more]

PMID: 23062248

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Project description:<h4>Background: </h4> The study of fat deposition in yaks of different gender plays a positive role in improving the meat quality and breeding of yaks. In this work, the characteristic of fat deposition in male and female yaks, and the regulations of gender difference to fat deposition in yaks were explored. <h4>Result: </h4> Compared with male yaks, the female yaks possessed higher or more body fat rate (BFR) of visceral except liver, fat content in muscle and liver and subcutaneous fat ( p < 0.05); the cholesterol (CH), triglyceride (TG), very low-density lipoprotein (VLDL), leptin (LEP) and cortisol (COR) in serum of female yaks were higher ( p < 0.05 ); meanwhile, the fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC), stearoyl-CoA desaturase (SCD) and diacylglycerol acyltransferase 1 (DGAT-1) in livers of female yaks were higher ( p < 0.05). The metabonomics analysis showed 13(S)-HODE, linoleic acid and linolenic acid and myo-inositol in subcutaneous fat of female yaks increased ( p < 0.05 ); meanwhile, the transcriptomic analysis the gene expressions of prenylcysteine oxidase 1 (PCYOX1), acyl-coenzyme a-cholesterol acyltransferase (ACAT), protein farnesyltransferase subunit beta (FNTB), apolipoprotein E (ApoE), DGAT2, very long chain fatty acids protein 6 (ELOVL6), NADP-dependent malic enzyme (ME1), SCD, acyl-CoA-binding protein (ACBP) and perilipin-5 (PLIN5), LEP, sterol regulatory element-binding protein 1 (SREBF1) upregulated in subcutaneous fat of female yaks ( p FDR < 0.05), whereas the gene expressions of CPT1, acetyl-CoA acyltransferase 1(ACAA1) and adipose triglyceride lipase (ATGL) downregulated ( p FD R < 0.01). <h4>Conclusion: </h4> The fat and cholesterol synthesis increased in liver of female yaks, and the fat transport in blood of female yaks increased too. In subcutaneous fat of female yaks, the high levels of myo-inositol activated the calcium signaling, following the increase of secretion in fat cell. Then, the high levels of LEP and 13(S)-HODE strengthened PPAR signal, and the fat synthesis, cholesterol synthesis, fatty acid biosynthesis of the linoleic and linolenic acid being the precursor increased, whereas lipolysis and fatty acid oxidation decreased by the regulation of downstream genes in PPAR signal. Meanwhile, SREBF1 also played an important part in the regulation of fat metabolism in yaks of different gender.

Dataset Information

Massage improves growth quality by decreasing body fat deposition in male preterm infants.

Objectives

Study design

Results

Conclusions

Publications

Massage improves growth quality by decreasing body fat deposition in male preterm infants.

Similar Datasets

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