Dataset Information

Antimicrobial rubrolides from a South African species of Synoicum tunicate.

ABSTRACT: The CH?Cl?-MeOH extract of a South African tunicate described as the new Synoicum globosum Parker-Nance sp. nov. (Ascidiacea, Aplousobranchia) was subjected to ¹H NMR-guided fractionation. This resulted in the identification of new 3?-bromorubrolide F (1), 3'-bromorubrolide E (2), 3'-bromorubrolide F (3), and 3',3?-dibromorubrolide E (4) and reisolation of known rubrolides E (5) and F (6), based on NMR spectroscopic and mass spectrometric data. Biological testing of both new and known members of this reported antimicrobial family of halogenated, aryl-substituted furanones indicated moderate antibacterial properties for 3'-bromorubrolide E (2), 3',3?-dibromorubrolide E (4), and rubrolide F (6) against methicillin-resistant Staphylococcus aureus (MRSA) and S. epidermidis.

SUBMITTER: Sikorska J

PROVIDER: S-EPMC3549467 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Antimicrobial rubrolides from a South African species of Synoicum tunicate.

Sikorska Justyna J Parker-Nance Shirley S Davies-Coleman Michael T MT Vining Oliver B OB Sikora Aleksandra E AE McPhail Kerry L KL

Journal of natural products 20121002 10

The CH₂Cl₂-MeOH extract of a South African tunicate described as the new Synoicum globosum Parker-Nance sp. nov. (Ascidiacea, Aplousobranchia) was subjected to ¹H NMR-guided fractionation. This resulted in the identification of new 3″-bromorubrolide F (1), 3'-bromorubrolide E (2), 3'-bromorubrolide F (3), and 3',3″-dibromorubrolide E (4) and reisolation of known rubrolides E (5) and F (6), based on NMR spectroscopic and mass spectrometric data. Biological testing of both new and known members of ...[more]

PMID: 23030848

Similar Datasets

Project description:BackgroundThe previous species list of South African Mantodea, published in 1998, was largely compiled from the literature and did not incorporate data from the many insect museum collections available in the country. It is estimated that approximately 120 species of Mantodea occur in South Africa; however, since no historical museum records were previously incorporated, the current information is considered to be outdated and not a true reflection of the Mantodea fauna within this region. A checklist of species is an important benchmark for any insect group, especially in light of the worldwide declines of insect diversity reported over the last decade. Checklists that provide accurate information on insect diversity, especially for groups, such as the Mantodea which could be under threat and thus could provide important information that can be used in determining the threat status of species, as well as to aid in their conservation in general.New informationThis paper provides an updated checklist of the praying mantids (Insecta, Mantodea) species of South Africa. While 120 species were previously reported to occur in South Africa, this paper reports 157 species in 64 genera that represent eight different superfamilies, 14 families and 22 subfamilies. Additionally, five species are reported for the first time to occur in South Africa. This species list was generated from the approximately 4000 specimen records of which 3558 records reside within South Africa. The remaining 732 records represent 14 other African countries. Occurrence records from two citizen-science platforms (iNaturalist and Gbif.org), were also incorporated in this study, adding 1880 species records in South Africa. The low number of specimens in the national collections indicate that this group of insects is poorly collected and highlights the lack of knowledge about South Africa's mantid fauna, as well as a lack of taxonomic expertise as 1532 museum specimens remain unidentified to species level.

Dataset Information

Antimicrobial rubrolides from a South African species of Synoicum tunicate.

Publications

Antimicrobial rubrolides from a South African species of Synoicum tunicate.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets