Ontology highlight
ABSTRACT:
SUBMITTER: Weidner T
PROVIDER: S-EPMC3549518 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Weidner Tobias T Dubey Manish M Breen Nicholas F NF Ash Jason J Baio J E JE Jaye Cherno C Fischer Daniel A DA Drobny Gary P GP Castner David G DG
Journal of the American Chemical Society 20120518 21
Extracellular biomineralization proteins such as salivary statherin control the growth of hydroxyapatite (HAP), the principal component of teeth and bones. Despite the important role that statherin plays in the regulation of hard tissue formation in humans, the surface recognition mechanisms involved are poorly understood. The protein-surface interaction likely involves very specific contacts between the surface atoms and the key protein side chains. This study demonstrates for the first time th ...[more]