Ontology highlight
ABSTRACT:
SUBMITTER: Hoshida Y
PROVIDER: S-EPMC3549578 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Hoshida Yujin Y Nijman Sebastian M B SM Kobayashi Masahiro M Chan Jennifer A JA Brunet Jean-Philippe JP Chiang Derek Y DY Villanueva Augusto A Newell Philippa P Ikeda Kenji K Hashimoto Masaji M Watanabe Goro G Gabriel Stacey S Friedman Scott L SL Kumada Hiromitsu H Llovet Josep M JM Golub Todd R TR
Cancer research 20090901 18
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to develop genomic-based classification for HCC have yielded highly divergent results, indicating difficulty in identifying unified molecular anatomy. We performed a meta-analysis of gene expression profiles in data sets from eight independent patient cohorts across the world. In addition, aiming to establish the real world applicability of a classification system, we profiled 118 formalin-fixed, paraffin-embedd ...[more]